Treatment of prurigo nodularis with dexamethasone-cyclophosphamide pulse therapy

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Dexamethasone-cyclophosphamide pulse therapy in pemphigus.

Fifty patients with pemphigus (45 pemphigus vulgaris, 5 pemphigus foliaceus) were treated with dexamethasone-cyclophosphamide pulse therapy. The pulse consisted of 136 mg dexamethasone dissolved in 5% dextrose given in a drip over a period of 1-2 hours on 3 consecutive days. In addition, 500 mg cyclophosphamide was added in the drip on the first day. Such pulses were given at monthly intervals....

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Systemic sclerosis and dexamethasone cyclophosphamide pulse therapy.

Sir, There have been quite a few instances where the physician or may be even a dermatologist (mis) advices a patient having systemic sclerosis that there is no satisfactory treatment for this disease, as has also been done in the paper ‘Therapeutic trials for systemic sclerosis: An update’ by Sardana and Garg.[1] Such patients often feel frustrated and disappointed, till another dermatologist ...

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Most patients with localized nodules should receive topical treatment first. But disappointing results or specific findings described here could necessitate additional or alternative options.

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Prurigo nodularis: a review.

Prurigo nodularis is a chronic condition characterized by a papulonodular pruriginous eruption of unknown aetiology. This condition is a difficult disease to treat and causes frustration to both the patient and the treating doctor. A variety of systemic conditions have been reported to be associated with prurigo nodularis. The mechanism by which these disorders may trigger prurigo nodularis is ...

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ژورنال

عنوان ژورنال: Indian Journal of Dermatology, Venereology, and Leprology

سال: 2016

ISSN: 0378-6323

DOI: 10.4103/0378-6323.174413